维吾尔族缺血性脑卒中影响因素病例对照研究

目的 研究影响新疆维吾尔族人群缺血性脑卒中发生的危险因素。方法 采用1:1配对病例对照研究方法,对100例维吾尔族缺血性脑卒中首发病人及相匹配的100名健康对照进行调查,采用Epdata3.0建立数据库及SAS9.0统计软件进行分析,筛选缺血性脑卒中的危险因素。结果 多因素Logistic回归分析结果显示,高文化程度(OR=0.26,95%CI=0.14～0.47)、休闲中中轻度活动(OR=0.05,95%CI=0.01～0.42)为缺血性脑卒中的保护因素;而患有高血压(OR=32.44,95%CI=4.39～239.99)、腰臀围比超标(OR=4.01,95%CI=1.19～13.45)及过去2个月经历负性生活事件(OR=12.97,95%CI=1.18～142.23)则为危险因素;血液中高白蛋白(OR=0.86,95%CI=0.75～0.99)及高密度脂蛋白(OR=0.32,95%CI=0.15～0.64)为保护因素。结论 影响新疆维吾尔族人群缺血性脑卒中发生危险因素较多,其特异性危险因素有腰臀围比超标和过去2个月经历负性生活事件。

A case-control study on influence factors of ischemic stroke in Uyghur population

Objective To explore the risk factors of ischemic stroke in the Xinjiang Uyghur population.Methods The method of 1:1 matched case-control study was used to investigate 100 Uyghur ischemic stroke cases of first onset and 100 healthy controls.SAS90 was used to analysis the data constructed by Epidata30.Results The high education level(odds ratio[OR]=0.26,95% confidense interval[CI]:0.14-0.47),mild leisure activity(OR=0.05,95%CI:0.01-0.42) were independent protective factors of ischemic stroke;the hype rtension history(OR=32.44,95%CI:4.39-239.99),abnorma lwaisthip ratio(OR=4.01,95%CI:1.19-13.45)and experience of negative life event in previous 2 months(OR=12.97,95%CI:1.18-142.23)were the risk factors of ischemic stroke.Album in content in blood(OR=0.86,95%CI:0.75-0.99)and high density lipid in blood(OR=0.32,95%CI:0.15-0.64)were the independent protective factors of ischemic stroke.Conclusion A bnorma lwaisthip ratio and experience of negative life event in previous 2 months are risk factors of ischemic stroke incident among Uyghur population in Hamicity.