| 2型糖尿病患者血清肿瘤坏死因子和唾液酸联合检测的临床意义 |
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| 引用本文： | 宋长祥. 2型糖尿病患者血清肿瘤坏死因子和唾液酸联合检测的临床意义[J]. 淮海医药, 2003, 21(1): 11-12 |
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| 作者姓名： | 宋长祥 |
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| 作者单位： | 江苏省连云港市第一人民医院,离休干部门诊,222002 |
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| 摘 要： | 目的 探讨血清 TNF和 SA含量在 2型糖尿病患者发生和发展中作用。方法 分别应用放免法和化学法测定 88例 2型糖尿病患者血清 TNF和 SA含量 ,并与 35名正常人作对照。结果 2型糖尿病患者血清TNF、SA含量则显著地高于正常人组 (P<0 .0 1) ,且与胰岛素水平呈明显的正相关 (r=0 .6 82 5 ,0 .6 2 6 3,P<0 .0 1)。结论 测定 2型糖尿病患者血清中 TNF、SA含量的变化对其观察病情的变化具有重要的临床价值
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| 关 键 词： | 糖尿病 非胰岛素依赖型 肿瘤坏死因子 唾液酸 胰岛素 |
| 文章编号： | 1008-7044(2003)01-0011-02 |
| 修稿时间： | 2002-03-31 |
Measurement of TNF,SA in serum from type 2 diabetes and their clinical significance |
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| SONG Chang xiang.. Measurement of TNF,SA in serum from type 2 diabetes and their clinical significance[J]. Journal of Huaihai Medicine, 2003, 21(1): 11-12 |
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| Authors: | SONG Chang xiang. |
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| Abstract: | Objective To explore the effect of serum tumor necrosis factor(TNF) and sialicacid(SA) on the development of type 2 diabetes.Methods TNF was detected by RLA and SA detected by chemistry in 88 patients with type 2 diabetes and 35 normal controls.Results The levels of TNF and SA concentration were obviously higher than those in normal controls( P <0.01) and correlated with the levels of insulin( r =0.6825,0.6263, P < 0.01 ).Conclusion Measuring serum TNF and SA might be the important parameters for clinical evaluation in patients with type 2 diabetes. |
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| Keywords: | Diabetes mellitus non insulin dependent Tumor necrosis factor Sialic acid Insulin |
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