Antimycotic 2-alkyldithio, 2-aralkyldithio, 2-aryldithiobenzamides |
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Authors: | T Modena F Pavanetto L Montanari M Mazza B Conti |
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Abstract: | Some 2-alkyldithio, 2-aralkyldithio, 2-aryldithio benzoic acids, their methyl esters and N-monosubstituted amides were prepared and tested in vitro against Candida albicans and Trichophyton mentagrophytes. Some N-monosubstituted amides displayed activities similar to those of clotrimazole and pyrrolnitrin. Against Candida albicans, N-monosubstituted amides exhibited a generally higher activity than the corresponding N-monosubstituted amides of 2,2'-dicarboxydiphenyldisulfide. |
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