| IDDM患者白细胞介素2和白细胞介素6的研究 |
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| 引用本文： | 曹仁贤,欧阳安.IDDM患者白细胞介素2和白细胞介素6的研究[J].中华内分泌代谢杂志,1994,10(4):208-210. |
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| 作者姓名： | 曹仁贤 欧阳安 |
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| 作者单位： | 衡阳医学院第一附属医院内科，河南医科大学第一附属医院内分泌科 |
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| 摘 要： | 测定ＩＤＤＭ患者１６例、ＮＩＤＤＭ患者２０例和正常对照组２７例的外周血单个核细胞产生白细胞介素２（ＩＬ－２）和白细胞介素６（ＩＬ－６）的能力。结果：ＩＤＤＭ患者ＩＬ－２水平较正常对照组和ＮＩＤＤＭ患者显著降低（ｐ＜０．００１），ＩＬ－６的水平显著升高（Ｐ＜０．００１）。ＮＩＤＤＭ患者ＩＬ－２和ＩＬ－６与正常对照组差异无显著性。提示ＩＤＤＭ患者ＩＬ－２和ＩＬ－６异常改变导致免疫功能紊乱。
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| 关 键 词： | IDDM，白细胞介素2，白细胞介素6 |
A STUDY ON INTERLEUKIN 2 AND 6 IN INSULIN-DEPENDENT DIABETES MELLITUS PATIENTS |
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| Cao Ren-xian,Ouyang An.A STUDY ON INTERLEUKIN 2 AND 6 IN INSULIN-DEPENDENT DIABETES MELLITUS PATIENTS[J].Chinese Journal of Endocrinology and Metabolism,1994,10(4):208-210. |
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| Authors: | Cao Ren-xian Ouyang An |
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| Institution: | Cao Ren-xian,Ouyang An Department of Internal Medicine,The First Affiliated Hospital,Hengyang Medical College,Hengyang 421001 |
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| Abstract: | Interleukin 2(IL-2)and interleukin
6(IL-6)production in peripheral blood monocytes (PBMNCs)was measured in 16
IDDMpatients,20 NIDDM patients and 27 controls. The results showed that the level of IL-2 in
IDDM patients was lower and the levelof IL-6 was higher than those of the control and the
NIDDM patients(P<0.001).Regarding the levels of IL-2 and IL-6, no differ-ence between NIDDM
patients and control patients was detected.These results suggest that the IL-and IL-6 of IDDM
have abnor-mal changes which induce immunological disorder. |
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| Keywords: | IDDM Interleukin-2 Interleukin-6 |
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