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中老年人高密度脂蛋白胆固醇与性激素的关系
引用本文:杨文英,郝景华.中老年人高密度脂蛋白胆固醇与性激素的关系[J].中华内分泌代谢杂志,1994,10(1):7-9.
作者姓名:杨文英  郝景华
作者单位:北京中日友好医院内分泌科,北京海淀医院内科,北京中日友好医院心内科,北京市宣武医院心内科
摘    要:对102例年龄≥45岁的中老年非糖尿病人群的高密度脂蛋白胆固醇(HDL-C)载脂蛋白A1(ApoA1)进行测定,并观察它们与性激素的关系。经逐步回归分析,结果显示了HDl-C与年龄、体重指数(BMI)、空腹血浆胰岛素(F-Ins)水平显著负相关,与雌二醇/睾丸酮(E2/T)比值呈显著正相关(P=0.0001),与T呈显著负相关(P=0.0001)。在调整年龄、BMI和INS、F后,E2/T比值是影响HDL-C水平的独立因素。ApoA1,作为因变量进行相同的分析得到了与HDL-C相似的结果。

关 键 词:高密度脂蛋白胆固醇,载脂蛋白A1,雌二醇,睾酮

RELATION BETWEEN SEX HORMONE AND HDL-C AND APO-A IN MIDDLE-AND OLD-AGED PEOPLE
yang Wen-ying.RELATION BETWEEN SEX HORMONE AND HDL-C AND APO-A IN MIDDLE-AND OLD-AGED PEOPLE[J].Chinese Journal of Endocrinology and Metabolism,1994,10(1):7-9.
Authors:yang Wen-ying
Abstract:The authors have studied the high density lipoprotein cholesterol(HDL-C)and apoprotein-A in102 non-diabetes mellitus casesolder than 45 years and observed the relation between the sex hormone level and these parameters. The results of stepwise regres-sive analysis revealed the following:HDL-C has significant negative correlation with age,BMI and fasting insulin;significant posi-tive correlation with estradiol-testosterone ratio and significant negative correlation with testosterone.After adjusting age,BMI andfasting insulin,the estradiol-testosterone ratio is an independent factor influencing the HDL-C level.With Apo-A as a dependentvariable,similar analytic method yields comparable results as can be obtained with HDL-C.
Keywords:HDL-C Apoprotein-A Estradiol  Testosterone  
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