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Steroid hormones modulate lipid spectrum in lysosomal membranes of skin fibroblasts
Authors:P V Sergeev  T V Ukhina  A V Semeikin  Yu S Akulov
Institution:(1) Department of Molecular Pharmacology and Radiobiology, Biomedical Faculty, Russian State Medical University, Moscow
Abstract:It is shown that estradiol and hydrocortisone modulate lipid composition and affect lipidprotein interaction in fibroblast lysosome membranes, which can promote enzyme release from lysosomes. These effects are particular mechanisms of hormone regulation of functional lysosome activity in the skin. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 125, No. 2, pp. 165–167, February, 1998
Keywords:fibroblasts                      steroid hormones                      lysosomes                      skin                      lipids
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