Steroid hormones modulate lipid spectrum in lysosomal membranes of skin fibroblasts |
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Authors: | P V Sergeev T V Ukhina A V Semeikin Yu S Akulov |
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Institution: | (1) Department of Molecular Pharmacology and Radiobiology, Biomedical Faculty, Russian State Medical University, Moscow |
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Abstract: | It is shown that estradiol and hydrocortisone modulate lipid composition and affect lipidprotein interaction in fibroblast
lysosome membranes, which can promote enzyme release from lysosomes. These effects are particular mechanisms of hormone regulation
of functional lysosome activity in the skin.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 125, No. 2, pp. 165–167, February, 1998 |
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Keywords: | fibroblasts steroid hormones lysosomes skin lipids |
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