Iodine-catalyzed synthesis of benzoxazoles using catechols,ammonium acetate,and alkenes/alkynes/ketones via C–C and C–O bond cleavage |
| |
| Authors: | Jasem Aboonajmi Farhad Panahi Mina Aali Hosseini Mahdi Aberi Hashem Sharghi |
| |
| Affiliation: | Department of Chemistry, College of Sciences, Shiraz University, Shiraz 71454 Iran, Fax: +98 7132280926, +98 7136137136 ; Department of Chemical and Materials Engineering, Faculty of Shahid Rajaee, Technical and Vocational University (TVU), Shiraz Branch, Shiraz Iran |
| |
| Abstract: | An efficient metal-free synthesis strategy of benzoxazoles was developed via coupling catechols, ammonium acetate, and alkenes/alkynes/ketones. The developed methodology represents an operationally simple, one-pot and large-scale procedure for the preparation of benzoxazole derivatives using molecular iodine as the catalyst.A metal-free one-pot multi-component method for the efficient synthesis of 2-aryl benzoxazoles via coupling of catechols, ammonium acetate and alkenes/alkynes/ketones using an I2–DMSO catalyst system is illustrated. |
| |
| Keywords: | |
|
|
