大学生男男性行为者对艾滋病暴露前预防知识知晓及其影响因素

目的 了解我国大城市大学生MSM对艾滋病暴露前药物预防（PrEP）知识知晓情况及其影响因素。方法 采用网上问卷调查方式收集北京、深圳、昆明三市的大学生中男男性行为者（MSM）的基本情况、行为学特征、艾滋病防治知识知晓、PrEP知识知晓情况，并以PrEP知识知晓为因变量，进行单因素和logistic回归模型多因素分析。结果 共调查293名大学生MSM，平均年龄为21.0(20.8～21.2)岁，本科生占91.1%。调查对象中男性伴数多于1个者占38.9%，每次性行为都使用安全套者占68.0%，近一年内29.4%未进行HIV检测。大学生MSM中艾滋病防治知识知晓率为 92.2%(270/293)，PrEP知识知晓率为34.5%，74.7%听说过PrEP； 53.6%认为PrEP作用是预防HIV，73.7%认为接受PrEP同时要使用安全套。多因素分析结果显示，近3个月每次同性行为使用安全套（OR=3.394,95% CI:1.179～9.773)，近一年内HIV检测次数大于2次（OR=2.181.95% CI:1.062～4.479）是大学生MSM知晓PrEP的影响因素。结论 大学生对于PrEP的正确认知仍不足，但出于对自身健康的关心，能主动获取PrEP相关的知识和信息，应结合高校内艾滋病防治知识宣传和健康教育,进行PrEP知识宣传和健康教育。

Status and influencing factors of knowledge awareness of HIV/AIDS pre-exposure drug prophylaxis(PrEP) of MSM among college students

Objective To understand the status and influencing factors of knowledge awareness ofHIV/AIDS pre-exposure drug prophylaxis(PrEP) ofmen who have sex with men(MSM)among college studentsin three cities(Beijing, Shenzhen and Kunming) of China. Methods Anonline survey was conducted among MSM of students in the three cities by using the questionnaires to collect their demographic information, sexual behavior characteristics, knowledge awareness of HIV/AIDS prevention, and PrEP. Single and multiple factor methods were used for the analysis. Results A total of 293 MSM were surveyed. The average age was 21.0(20.8-21.2) years, and 91.1% were undergraduates. 38.9% of the respondents had more than one sexual partner; 68.0% used condom for each time of sex. 29.4% had not received HIV testing in the past year. The knowledge awareness rates of HIV/AIDS prevention and PrEP were 92.2%(270/293), and 34.5% respectively. 74.7% heard of PrEP. 53.6% reported that PrEP could prevent HIV; 73.7% reported that condom should be used while taking PrEP. The results of multivariate analysis showed that condom use for each homosexual act in the past 3 months(OR=3.394,95%CI:1.179-9.773) and more than 2 times of HIV testing in the past year(OR=2.181.95%CI:1.062-4.479) were influential factors for PrEP knowledge awareness among the MSM of students. Conclusion Knowledge awareness of PrEP among students, esp. the MSM is insufficient. However, out of concern for their own health, they are able to actively acquire knowledge and information related to PrEP. PrEP knowledge promotion and health education should be carried out in combination with AIDS prevention knowledge and health education in colleges and universities.