安徽省医学专科生体力活动与抑郁症状的关联

目的 探讨体力活动（physical activity，PA）与医学专科生抑郁症状的关联及其性别差异。方法 采取整群抽样的方法，于2019年11-12月选取安徽省2所医学专科院校8 198名在校生为研究对象，使用国际体力活动问卷短卷（IPAQ-SF）、抑郁自评量表（SDS）评估PA和抑郁症状。应用限制性立方样条分析PA与抑郁症状的剂量-反应关系，据此将PA分成4组；应用非条件logistic回归模型分析PA与抑郁症状的关系。结果 PA与抑郁症状呈非线性的剂量-反应关系（P＜0.001），按PA分为4组:＜570 MET-min/week组（1636例）、570～1331.5 MET-min/week组（2131例）、＞1331.5～1848 MET-min/week组（1075例）、＞1848 MET-min/week组（2692例）。7 534名医学专科生抑郁症状检出率为16.1%，其中男生抑郁症状检出率为19.6%，女生抑郁症状检出率为14.9%，差异有统计学意义（〖XC五号.EPS;P〗=24.20，P＜0.001）。以＞1848 MET-min/week为参照组，与参照组相比，在总人群以及男、女生中，PA＜570 MET-min/week均与抑郁症状风险增加有关（OR=1.50，95%CI: 1.28～1.77；OR=1.90，95%CI: 1.41～2.55；OR=1.36，95%CI: 1.11～1.65）。结论 PA与抑郁症状呈非线性关系，增加适当的体力活动有利于大学生抑郁症状的防控。

The relationship between physical activity and depressive symptoms among medical college students in Anhui Province

To explore the dose － response relationship between physical activity ( physical activity，PA) anddepressive symptoms and its sex differences among medical college students. Methods A cluster sampling method wasadopted，and 8 198 current students were recruited from two medical colleges in Anhui Province from November to December2019. The International Physical Activity Questionnaire Short Form and Self － Ｒating Depression Scale were used to assess PAand depressive symptoms. Participants were divided into four groups based on the dose － response relationship between PA anddepressive symptoms analyzed by the restricted cubic spline. Unconditional logistic regression model was used to analyze theassociation between PA and depressive symptoms. Ｒesults PA and depressive symptoms showed a non － linear dose －response relationship ( P ＜ 0. 001) . According to the level of PA，it was allocated into four groups: ＜ 570 MET － min /week( n = 1 636) ，570 － 1 331. 5 MET － min /week ( n = 2 131) ，＞ 1 331. 5 － 1 848 MET － min /week ( n = 1 075) ，＞ 1 848 MET－ min /week ( n = 2 692) ，and the numbers of these subjects were 1 636，2 131，1 075 and 2 692，respectively. Theprevalence rate of depressive symptoms in 7 534 medical college students was 16. 1% ，among which the prevalence rate ofdepressive symptoms in boys was 19. 6% and that in girls was 14. 9% ( χ2 = 24. 20，P ＜ 0. 001) . Compared with the referencegroup ( ＞ 1 848 MET － min /week) ，Participants with PA ＜ 570 MET － min /week had an increased risk for depressivesymptoms in the general population and males and females ( OＲ = 1. 50，95% CI: 1. 28 － 1. 77; OＲ = 1. 90，95% CI: 1. 41 －2. 55; OＲ = 1. 36，95% CI: 1. 11 － 1. 65) . Conclusion PA is non － linearly connected with depressive symptoms. Increasingappropriate physical activity is conducive to the prevention and control of depressive symptoms in college students.