| 氨基酸鳌合钙联合骨化三醇治疗肾性骨病的临床观察 |
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| 引用本文： | 徐文蔚,刘欣颖,毛佩菊.氨基酸鳌合钙联合骨化三醇治疗肾性骨病的临床观察[J].现代医药卫生,2008,24(24):3650-3651. |
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| 作者姓名： | 徐文蔚 刘欣颖 毛佩菊 |
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| 作者单位： | 上海市长宁区中心医院肾内科 |
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| 摘 要： | 目的:探讨治疗继发性甲状旁腺功能亢进(SHPT)骨病的方法.方法:对48例长期血液透析的慢性肾功能衰竭患者分别给予骨化三醇及骨化三醇联合钙剂治疗,观察血清钙、磷、钙磷乘积、甲状旁腺激素(PTH)水平变化,并对两种治疗方法的结果进行比较.结果:两种治疗均可显著增加血清钙水平,降低血清磷水平,骨化三醇加钙剂治疗的疗效更为显著(P＜0.01).结论:钙荆加骨化三醇治疗SHPT骨病优于单用骨化三醇.
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| 关 键 词： | 肾性骨病 骨化三醇 钙 钙磷代谢障碍 |
Clinical observation of calcium amino and chelate combined with calcitriol in the treatment of renal osteopathy |
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| XU Wen-wei,LIU Xin-ying,MAO Pei-ju.Clinical observation of calcium amino and chelate combined with calcitriol in the treatment of renal osteopathy[J].Modern Medicine Health,2008,24(24):3650-3651. |
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| Authors: | XU Wen-wei LIU Xin-ying MAO Pei-ju |
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| Abstract: | Objective:To investigate the therapeutic method of secondary hyperparathyroidism(SHPT) osteopathy.Methods:48 chronic renal failure patients undergoing long-term hemodialysis were treated with calcitriol or calcium combined with calcitriol.The lev-els of serum calcium,phosphorus,calcium and phosphorus product and parathyroid hormone(PTH) were observed respectively,and the results of two methods were compared.Results:The level of serum calcium increased significantly in both kinds of therapeutic method,while the level of serum phosphorus decreased,but the curative effect of calcitriol combined calcium was more significant(P<0.01).Con-clusion:Calcium combined with calcitriol in treatment SHPT osteopathy is better than calcitriol alone. |
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| Keywords: | Secondary hyperparathyroidism osteopathy Calcitriol Calcium Phosphorus and calcium metabolism disorders |
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