急性期脑卒中患者抑郁发生情况及相关因素研究

目的 对脑卒中后发生抑郁患者进行发病率及多种相关因素的研究,期望对这些患者的早期诊断和干预治疗提供帮助.方法 采用病例一对照研究方案.选用符合标准的所有脑卒中住院患者,抑郁患者为病例组,其余患者为对照组,对各相关因素进行统计学分析.结果 共调查116例患者,最后能够配合完成所有调查任务的有114例.抑郁发病人数为54例,占47.4％.单因素分析发现:神经功能缺损程度,日常生活能力指数,婚姻,卒中性质,病程与抑郁发生有关.多因素Logistic回归分析显示:神经功能缺损程度,日常生活能力是影响抑郁发生的主要因素.结论 神经功能缺损程度为脑卒中后抑郁的危险因素,日常生活能力为保护因素.

Depression in patients with acute stroke and related factors

Objective This research was designed to determine the morbidity and various correlation factors associated with the post--stroke depression for the purpose of early diagnosis and intervention for these patients. Methods A case--control study program was used. Eligible hospitalized stroke patients were dived into a symptomatic group with depressed patients and a control group with the remaining. All relevant factors were statistically analyzed. Results There were 116 patients surveyed with 114 patients who completed the study. Depressive inpatients were 54 cases, accounting for 47.4%. The univariate analysisshowed that depression was associated with neurological impairment, ADL index, marriage, property of stroke, course of disease. Logistic regression analysis showed that neurological ira- pairment and ADL index were the main factors. Conclusions factor, whereas daily living skills is the protective factor.