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新疆家犬体内存在细粒棘球绦虫G1(羊)株和G6(骆驼)株的分子证据
引用本文:张亚楼,温浩,马旭东,苗玉清,林仁勇,王星,卢晓梅. 新疆家犬体内存在细粒棘球绦虫G1(羊)株和G6(骆驼)株的分子证据[J]. 中国病原生物学杂志, 2005, 18(5): 333-335
作者姓名:张亚楼  温浩  马旭东  苗玉清  林仁勇  王星  卢晓梅
作者单位:新疆包虫病基础医学重点实验室,新疆,乌鲁木齐,830054
基金项目:This study was supported by the Key Lab Foundation of Xinjiang(No.XJDX0202-2003-03).
摘    要:目的收集家犬体内的细粒棘球绦虫成虫以建立新疆棘球蚴病的分子流行病学资料. 方法对家犬体内成虫细胞色素c氧化酶Ⅰ基因序列进行测定以确定其亚株型. 结果所有感染犬体内成虫的基因型为G1型.特别是1条家犬体内发现存在细粒棘球绦虫G1(羊)株和G6(骆驼)株混合感染的情况. 结论在新疆阻断羊犬和羊骆驼循环圈是预防棘球蚴病的重要措施.作为终末宿主的家犬与人类的感染密切相关,对感染犬的管理应该加强.

关 键 词:细粒棘球绦虫  细胞色素c氧化酶Ⅰ基因  棘球蚴病
文章编号:1001-6627(2005)05-0333-03
修稿时间:2005-06-22

MOLECULAR EVIDENCE OF SHEEP(G1) AND CAMEL(G6) STRAINS OF ECHINOCOCCUS GRANULOSUS IN XINJIANG, CHINA
ZHANG Ya-lou,Jean-Mathieu BART,WEN Hao,MA Xu-dong,MIAO Yu-qing,LIN Ren-yong,WANG Xing,LU Xiao-mei. MOLECULAR EVIDENCE OF SHEEP(G1) AND CAMEL(G6) STRAINS OF ECHINOCOCCUS GRANULOSUS IN XINJIANG, CHINA[J]. Journal of Pathogen Biology, 2005, 18(5): 333-335
Authors:ZHANG Ya-lou  Jean-Mathieu BART  WEN Hao  MA Xu-dong  MIAO Yu-qing  LIN Ren-yong  WANG Xing  LU Xiao-mei
Affiliation:ZHANG Ya-lou,Jean-Mathieu BART,WEN Hao~
Abstract:Objective 17 dogs' adult worms of Echinococcus granulosus were collected in order to establish some epidemiological molecular information in Xinjiang. Methods The sequencing of the mitochondrial cytochrome c oxidaseⅠ( COⅠ) gene of several adult worm from dogs was performed to confirm genotype of the E. granulosus strains. Results The most part (17) of adult worms' genotype was sheep strain (G1). Especially, the mixed infection of the camel strain G6 and sheep strain G1 were uniquely found in one dog. Conclusion The results confirm the importance of the prophylaxis measures in order to disrupt the cycle of sheep-dog and camel-dog transmission in Xinjiang. Nevertheless, the supervision of dog infection should be reinforced because this definitive host constitutes an important link with human contamination.
Keywords:Echinococcus granulosus  cytochrome c oxidase Ⅰ gene (COⅠ)  hydatidosis
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