先天性唇、腭裂对患儿呼吸系统顺应性的影响

目的 探讨先天性辰、腭裂对患儿呼吸系统顺应性（ＣＴ）的影响。方法 唇裂或腭裂病儿２４０例（观察组），非唇腭裂病儿６０例（对照组）均为择期手术患，按年龄段：１～１２月、１～３岁、４～７岁、８～１２岁，各分为５个亚组。全麻诱导气管内插管后，行机械通气，保持ＰＥＴＣＯ２４～４．６ｋＰａ，用Ｄａｔｅｘ Ｕｌｔｉｍａ监测仪测定ＣＴ。结果 与非唇裂同一年龄组ＣＴ值相比，唇裂各年龄组、腭裂１～１２月及１～３岁组

Influence of congenital cleft lip or cleft palate on total respiratary compliance in child

Objective To investigate the influence of congenital cleft lip or cleft palate on total respiratary compliance (C T) in child.Methods Sixty children without congenital malformation (control group) and 240 children with congenital cleft lip or cleft palate (test group), scheduled for selected operation, were divided into 5 subgroups according to the age range: 1 12 months,1 3 years,4 7 years and 8 12 years,respectively. With the mechnical ventilation following intratracheal intubation after anesthesia induction, P ET CO 2 was maitained at 4 4.6kPa. The C T was measured with Datex Ultima monitor.Results Compared with the control level in the same age subgroup, C T remained unsignificant changes in all subgroups of cleft lip and in 1 12 months and 1 3 years subgroups of cleft palate, but decreased significantly in 4 7 years and 8 12 years subgroups of cleft palate(P<0.01). There were not significant differences in ratio of C T to functional residual capacity(FRC) among all control or cleft lip subgroups. As compared with that in 1 12 months subgroup of cleft palate , the C T/FRC ratio decreased markedly in 4 7 years and 8 12 years subgroups(P<0.01).Conclusions C T of child with cleft palate reduces progressively with increasing age , so the repair of the palate should be performed at its early stage.