高尿酸血症相关因素调研及其中医证候学研究

目的：通过高尿酸血症患者相关因素调查，探索其与中医证候之间的关系，并确定基本证候类型，为中医辨证治疗提供依据。方法：采用回顾与前瞻性相结合研究方法，以高尿酸血症诊断标准选择病例，按照预先制定的临床研究表格对每份病例进行调查，调查结束后进行统计学处理。结果：临床共收集原发性高尿酸血症病例109例，研究结果显示：男性发病率明显高于女性，高龄患者发病率明显增加，冠心病以及高血压患者高尿酸血症发病率明显高于其他疾病；尿酸水平与血脂、体质量指数、饮酒关系不明显；气虚血瘀为高尿酸血症患者临床主要证候。结论：气虚血瘀扶湿是高尿酸血症患者临床主要证候；其发病与性别、年龄、冠心病、高血压关系密切；与高血脂、肥胖、饮酒关系不明确。

Research on Risk Factors of Hyperuricemia and Its Syndrome Differentiation in Traditional Chinese Medicine

Objective:To supply the reliable evidence for a further research of the TCM syndrome of hyperuricemia and treating it with traditional Chinese medicine,we try to verification the risk factors and to research TCM syndrome differentiation for diagnosis in patients with hyperuricacidemia.Methods: We selected cases according to the standard of hyperuricacidemia's diagnose and adopted the method of retrospective and prospective analysis.Each of cases was investigated and filled in the form.These data were processed through statistical method in the end.Results: Clinical investigation selected 109 cases patients with hyperuricacidemia.First,male group incidence rate was higher than female.Second,incidence rate was increasing with age(r=0.826 p<0.05).Third,CAD and hypertension group had higher incidence rate than any other diseases.Fourth,the level of uric acid did not seem to be related with hyperlipemia,BMI and drinking alcohol.Fifth,qi-deficiency and blood stasis were the main TCM syndrome in patients with hyperuricacidemia.Conclusion: The most prevalent TCM syndrome type in hyperuricacidemia was qi deficiency and blood stasis.Primary hyperuricacidemia risk factors are age,sex,CAD and hypertension.Hyperuricacidemia is irrelated with hyperlipemia,blood-fat and drinking alcohol.