Protective Effect of Eecdysterone on the PC12 Cell CytotoxicityInduced by beta-amyloid 25-35 |
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作者姓名: | YANGSu-Fen WUZhong-Jun YANGZheng-Qin LIYu WuQin ZHOUQi-Xin SHIJing-Shan |
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作者单位: | [1]DepartmentofPharmacology,ZunyiMedicalCollege,Zunyi563003 [2]DepartmentofPharmacology,ChongqingMedicalUniversity,Chongqing400016 |
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摘 要: | Objective. To study the effect of ecdysterone (ECR) on beta - amyloid peptide fragment 25-35 ( Aβ25-35 )-induced PC12 cell cytotoxicity, and further to expore its mechanism. Methods: PC12 survial was monitored by LDH release and 3-(4, 5-dimethylthiazol-yl-2, 5-diphenyhetrazolium bromide (MTT) assays. The content of malondi-
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关 键 词: | 保护作用 脑电图 PC12 细胞毒素 β-淀粉样肽 ECR |
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