多指标联合测定在胸腔积液中的诊断价值

目的探讨联合检测腺苷脱氢酶(ADA)、结核抗体(TB-Ab)、癌胚抗原(CEA)、铁蛋白(Fer)、C反应蛋白(CRP)对胸腔积液的鉴别诊断价值。方法收集临床已确诊的胸腔积液标本86例(结核性胸腔积液32例、恶性胸腔积液35例和化脓性胸腔积液19例),检测胸腔积液中ADA、TB-Ab、CEA、Fer和CRP的数值,并进行各组间统计学分析。结果结核性胸腔积液组ADA活性,TB-Ab阳性率明显高于恶性和化脓性胸腔积液;化脓性胸腔积液组CRP明显高于恶性和结核性胸腔积液组;恶性胸腔积液组CEA、Fer明显高于化脓性和结核性胸腔积液组。结论 ADA、TB-Ab的检测对结核性胸腔积液有较高的实用价值。CRP检测对化脓性胸腔积液有较大的价值。CEA和Fer的联合检测对恶性胸腔积液有很大的实用价值。

The diagnostic value of joint determination of multiple indices in pleural effusion

Objective To investigate the differential diagnostic value of joint determination of ADA,TB-Ab,CEA,Fer and CRP in pleural effusion diagnosis.Methods 86 clinical confirmed pleural effusion samples （32 tuberculous pleural effusion cases,35 malignant pleural effusion cases and 19 purulent pleural effusion cases） were collected,at the same time,the datas of ADA,TB-Ab,CEA,Fer and CRP were inspected and statistical analysis for different groups was conducted.Results The activity of ADA and the positive rate of TB-Ab were significantly higher than that in malignant and purulent pleural effusion groups.The CRP in purulent pleural effusion group was higher than that of malignant and tuberculous pleural effusion groups.The CEA and Fer in malignant pleural effusion group were higher than that in purulent and tuberculous pleural effusion groups.Conclusion The determination of ADA and TB-Ab has a high practical value for tuberculous pleural effusion.The CRP determination is valuable for purulent pleural effusion.The joint determination of CEA and Fer has great practical value for malignant pleural effusion.