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Quantification of Clostridium difficile in antibiotic-associated-diarrhea patients
Authors:Naaber Paul  Stsepetova Jelena  Smidt Imbi  Rätsep Merle  Kõljalg Siiri  Lõivukene Krista  Jaanimäe Liis  Löhr Iren H  Natås Olav B  Truusalu Kai  Sepp Epp
Institution:Department of Medical Microbiology, Stavanger University Hospital, Postbox 8100, 4068 Stavanger, Norway. napa@sus.no
Abstract:Comparing culture- and non-culture-based methods for quantifying Clostridium difficile in antibiotic-associated-diarrhea patients, we found that the real-time PCR method correlated well with quantitative culture and was more sensitive. A positive association between the population levels of C. difficile and the presence of its toxins was found.
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