多发性硬化298个造影增强病灶特点

目的　了解多发性硬化 (MS)增强磁共振成像 (MRI)病灶的特点。方法　选择确诊MS186例 ,检查增强头颅MRI,发现阳性病灶后 ,每 (4± 1)周 1次头颅钆喷替酸葡甲胺造影剂 (GD)增强MRI ,观察了 2 98个病灶的形态及变化情况。结果　造影病灶形态可为圆形、卵圆形、环形、弧形、点状和不规则形。 2 98个GD增强病灶中 ,2 0 7个 (6 9 5 % )在发现后的 4周内消失 ,2 5 1个 (84 2 % )于 8周内消失 ,2 72个 (91 3% )于 12周内消失 ,3个病灶持续存在 2年以上。结论　MSGD增强MRI病灶绝大多数在 4周内消失 ,少数可持续 2年以上 ;为了观察MS脑内增强MRI病灶的变化 ,有条件的最好每月检查 1次增强MRI。

The characteristics of enhanced gadolinium DTPA brain magnetic resonance images in 298 multiple sclerosis patients

Objective To investigate the characteristics of enhanced brain magnetic resonance imaging (MRI) with gadolinium-DTPA(GD)in patients with multiple sclerosis(MS).Methods Brain enhanced MRI were studied in 186 patients with clinically definite multiple sclerosis. 298 MRI enhanced lesions were followed every 4 weeks and the study lasted 3 months to 2 years. Results Of the 298 enhanced MRI lesions 207 (69.5%) lasted less than 4 weeks, 251(84.2%) 8 weeks, and 272(91.3%) 12 weeks. There were 3 lesions lasting more than 2 years. Round, oval, ring form, arcuate, spotty, or irregular MRI GD enhanced lesions were found in our MS data.Conclusions Most of the MRI GD enhanced lesions disappear in 4 weeks. Very few can last more than 2 years. So it is necessary to perform the GD enhanced MRI in 4 weeks for studying MS intracranial GD enhanced lesions. The DA enhanced MRI lesions in MS may be round, oval, ring form, arcuate, spotty or irregular.