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晚期胃癌出口癌性狭窄应用内镜局部注射抗癌药物的疗效观察
引用本文:李光,余拉结,刘舜贤,汤如卿.晚期胃癌出口癌性狭窄应用内镜局部注射抗癌药物的疗效观察[J].医学综述,2008,14(13):2073-2074.
作者姓名:李光  余拉结  刘舜贤  汤如卿
作者单位:广东汕头市龙湖人民医院消化内科,广东,汕头,515041
摘    要:目的总结晚期胃癌或残胃癌出口癌性狭窄内镜注射治疗的疗效。方法对43例晚期胃癌或残胃癌出口癌性狭窄患者根据患者意愿分为2组,治疗组(n=23)经内镜用高渗钠联合化疗药注入瘤体基底部及周边,每周1次,连续6周。对照组(n=20)采用MAF方案即丝裂霉素、多柔比星、5-氟尿嘧啶]常规化疗。结果两组疗效、生存期、不良反应及并发症情况比较,差异均有统计学意义(P<0.05)。结论经内镜注射药物对晚期胃癌或残胃癌伴出口癌性狭窄是安全有效的姑息疗法,能重建腔道,解除梗阻,改善症状,延长生存期,且不良反应少等优点。

关 键 词:内镜  局部注射  晚期胃癌  残胃癌  癌性狭窄

The Observation of Therapeutic Effect of Local Chemotherapeutic Drug Injection Through Endoscope on Advanced Gastric Cancer
LI Guang,YU La-jie,LIU Shun-xian,TANG Ru-qin.The Observation of Therapeutic Effect of Local Chemotherapeutic Drug Injection Through Endoscope on Advanced Gastric Cancer[J].Medical Recapitulate,2008,14(13):2073-2074.
Authors:LI Guang  YU La-jie  LIU Shun-xian  TANG Ru-qin
Institution:LI Guang,YU La-jie,LIU Shun-xian,TANG Ru-qin.(Department of Gastroenterology,Longhu People\'s Hospital,Shantou 515041,China)
Abstract:Objective To summarize the experience of local chemotherapeutic drug injection through endoscope on advanced gastric cancer or cancerous stricture after gastric cancer operation.Methods 43 patients of advanced gastric cancer or cancerous stricture after gastric cancer operation were divided not-random into 2 groups; the treatment group(n=23) was administered local 10%Sodium Chloride plus chemotherapeutic drug injection through endoscope and the control group(n=20) was administered general chemotherapy(MAF)....
Keywords:Endoscope  Local injection  Advanced gastric cancer  Cancerous stricture  
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