| K88抗原基因研究进展(文献综述) |
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| 引用本文： | 吴雅旭.K88抗原基因研究进展(文献综述)[J].军事医学科学院院刊,1987(3). |
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| 作者姓名： | 吴雅旭 |
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| 作者单位： | 军事医学科学院基础医学研究所 |
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| 摘 要： | K88抗原是存在于肠毒性大肠杆菌表面的一种伞毛蛋白质。借伞毛的作用,肠毒性大肠杆菌可以吸附到仔猪小肠上皮细胞粘膜上,并在那里增殖,分泌肠毒素,引起仔猪腹泻、死亡。K88抗原是由约50md的大质粒编码的,通过重组和突变技术,对它们的性质进行了研究。
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| 关 键 词： | K88抗原基因 肠毒性大肠杆菌 伞毛蛋白质 |
PROGRESS IN THE STUDY OF THE K88 ANTIGEN GENE |
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| Wu Yaxu.PROGRESS IN THE STUDY OF THE K88 ANTIGEN GENE[J].Bulletin of the Academy of Military Medical Sciences,1987(3). |
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| Authors: | Wu Yaxu |
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| Abstract: | K88 antigen is a fimbria protein on the surface of enterotoxigenic Escherichia coli. After the specific adherence of K88 antigen to porcine small intestinal mucosa, pathogenic bacteria begin to proliferate, secrete enterotoxin and cause diarrhea and even death of the animal. The genetic determinants for K88 antigen production are carried on a 50-megadalton plasmid. Their characteristics were studied by recombination and mutation technique. |
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| Keywords: | K88 antigen gene enterotoxigenic E coli fimbria protein |
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