| CCL20及DCs在慢性阻塞性肺疾病患者诱导痰中的变化及意义 |
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| 引用本文： | 符丹丹,欧阳瑶,薛令合. CCL20及DCs在慢性阻塞性肺疾病患者诱导痰中的变化及意义[J]. 贵州医药, 2011, 35(5): 408-411. DOI: 10.3969/j.ISSN.1000-744X.2011.05.005 |
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| 作者姓名： | 符丹丹 欧阳瑶 薛令合 |
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| 作者单位： | 遵义医学院附属医院呼吸一科,563003 |
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| 基金项目： | 黔科合SY字[2009]3053 |
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| 摘 要： | 目的 检测慢性阻塞性肺疾病(COPD)患者诱导痰中CC亚族趋化因子配体20(CCL20)的含量,分析CCL20在COPD发病机制中的作用.方法 以COPD患者为研究对象,并以无COPD者健康人作为对照,采用沙丁胺醇加高渗盐水超声雾化吸八方法诱导排痰,ELISA法检测CCL20的含量;同时,常规方法测定肺功能FEV1%及...
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| 关 键 词： | 慢性阻塞性肺疾病 CCL20 诱导痰 肺功能 |
Composite resin Curing Microleakage Time Cavity |
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| Fu Dandan,Ou Yangyao,Xue Linghe. Composite resin Curing Microleakage Time Cavity[J]. Guizhou Medical Journal, 2011, 35(5): 408-411. DOI: 10.3969/j.ISSN.1000-744X.2011.05.005 |
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| Authors: | Fu Dandan Ou Yangyao Xue Linghe |
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| Affiliation: | .Department of Respiration,The Affiliated Hospital of Zunyi Medical College,563003,China. |
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| Abstract: | Objective To investigated CC chemokine ligand 20(CCL20) in the pathogensis of chronic obstructive pulmonary disease(COPD) through the change of CCL20 in the induced sputum of patients with COPD.Methods CCL20 were analyzed with ELISA in the sputum collected from COPD groups,cigarette smoke groups and control groups.FEV1% and FEV1/FVC were determined.ResultsCCL20 in the GOLD I～IV of COPD groups showed the upregulation of CCL20,compared with CCL20 in cigarette smoke groups and control groups.There was negative correlation between CCL20 and FEV1%(r=-0.913,P<0.01).Conclusion The significantly upregulation of CCL20 in the patients with COPD and the positive correlation between CCL20 and the stage of COPD show that CCL20 maybe contribute to the inflammatory reaction of COPD. |
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| Keywords: | CCL20 |
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