~(18)F-FDG符合线路SPECT/CT显像在肺癌术后随访中价值

目的探讨18氟-脱氧葡萄糖(~(18)F-FDG)符合线路单光子发射计算机断层成像术SPECT/CT显像在肺癌术后随访中的应用价值。方法回顾性分析2014年3月-2015年5月我院收治的56例行肺癌根治术的肺癌患者的临床资料,病例患者术后均得到有效随访,以术后病理结果为金标准,评估~(18)FFDG符合线路SPECT/CT显像在肺癌术后随访中的应用价值。结果残端复发、残端复发合并转移、单个病灶、多发转移及胸部未见明显复发转移征象患者例数分别为14、9、4、13、12;~(18)FFDG符合线路SPECT/CT显像诊断肺癌术后复发灵敏度为93.18%(41/44),特异性为75.00%(9/12),准确性为83.93%(47/56),阳性预测值为93.18%(41/44),阴性预测值75.00%(9/12)。结论~(18)F-FDG符合线路SPECT/CT显像在肺癌中诊断有一定应用价值,对肺癌患者术后随访复发诊断价值较高,为临床医师制定辅助化疗方案提供重要参考。

The Value of18F-FDG Coincidence SPECT/CT Imaging in the Follow-up after Lung Cancer Operation

Objective To evaluate the application value of18F-fluorodeoxyglucose (18F-FDG) coincidence single photon emission computed tomography (SPECT/CT) imaging in the follow up after lung cancer operation.Methods The clinical data of 56 patients with lung cancer who underwent radical resection in our hospital between March 2012 and May 2013 were retrospectively analyzed. All cases were effectively followed up after operation. With postoperative pathological results as golden standard, the application value of18F-FDG coincidence SPECT/CT imaging in follow-up after lung cancer operation was evaluated.Results The number of patients with recurrent residual, recurrent residual complicated with metastatic lesions, single lesion, multiple metastases, without obvious recurrence and metastasis in chest were 14, 9, 4, 13 and 12 respectively. The sensitivity, specificity and accuracy of18F-FDG coincidence SPECT/CT imaging in the diagnosis of recurrent lung cancer were 93.18% (41/44), 75.00% (9/12) and 83.93% (47/56), respectively. The positive and negative predictive values were 93.18% (41/44) and 75.00% (9/12) respectively.Conclusion18F-FDG line SPECT/CT imaging is of certain value in the diagnosis of lung cancer, and the value in the diagnosis of follow-up recurrence after operation is high, which provides important references for clinical physicians to develop adjuvant chemotherapy program.