胎儿肺部在MRI上的序列探讨及临床应用

目的探讨胎儿肺部在MRI上寻找最佳的成像序列,研究胎儿肺部成像在MRI中的临床应用。方法对54例中、晚期孕程的孕妇行SSh-T2WI及B-FFE扫描,评价两序列在胎儿肺部的图像质量、模糊程度、信噪比(SNR)及对比噪声比(CNR)等。结果在分级评价上SSh-T2WI序列在胎儿肺部均获得较高评分。在定量分析上,正常组胎儿左肺右肺在SSh-T2WI序列上分别是(1.87±0.33)和(1.92±0.29),B-FFE序列是(1.33±0.39)和(1.31±0.31)。病变组胎儿左肺右肺在SSh-T2WI序列上分别是(1.83±0.29)和(1.80±0.22),B-FFE序列是(1.30±0.22)和(1.32±0.25)。胎儿肺部与胎儿肝脏的CNR SSh-T2WI序列为(1.68±0.8)比B-FFE序列(1.01±0.71)。结论在MRI检查中SSh-T2WI序列能够清晰显示胎儿肺部及胎盘母体等的解剖结构,获得的图像具有较高的图像对比度,可作为胎儿肺部成像的首选序列。MRI能够清晰准确显示胎儿肺部及周围脏器等的细微结构,能直观、准确的诊断出胎儿呼吸系统疾病。

Study on the MRI Sequence of Fetal Lung and Its Clinical Application

Objective To explore the best imaging sequence of fetal lung in MRI, and to study the clinical application of fetal lung imaging in MRI.Methods SSh-T2WI and B-FFE scans of 54 pregnant women with middle and late pregnancy were performed to evaluate the image quality, blur degree, signal to noise ratio (SNR) and contrast noise ratio (CNR) of fetal lung in the two series.Results SSh-T2WI sequences obtained higher scores in fetal lungs in grading evaluation.In quantitative analysis, normal fetal left lung and right lung in the SSh-T2WI sequence were (1.87±0.33) and (1.92±0.29), (1.33±0.39) and B-FFE sequence is (1.31±0.31). The fetal left lung right lung in the lesion group was (1.83±0.29) and (1.80±0.22) on the SSh-T2WI sequence, and the B-FFE sequence was between (1.30±0.22) and (1.32±0.25). The CNR SSh-T2WI sequence of fetal lung and fetal liver was (1.68±0.8) than B-FFE's (1.01±0.71).Conclusion SSh-T2WI sequence in MRI examination can clearly show the anatomy of fetal lung and placenta of the obtained images with high image contrast, can be used as the preferred sequence of fetal lung imaging.MRI can clearly show the fine structure of fetal lungs and surrounding organs, can directly and accurately diagnosis of fetal respiratory system disease.