痛风患者足部痛风石沉积特点的双能量CT研究

目的应用双能量CT对足部痛风石常见沉积部位进行分析,并对痛风发病机制进行探讨研究。方法回顾性分析56例痛风患者的足部双能量CT扫描检查资料。将根据痛风石沉积部位分为关节组、韧带/肌腱组,并分别对其进行记录、分析。结果 56例患者中双能量CT共发现51例患者有痛风石沉积。关节组最常见受累部位为第一跖趾关节(75%,73/198),其次是踝关节(33.9%,32/198)。韧带/肌腱组中最常见受累部位依次是跟腱(39.3%,37/99)、腓骨肌腱(16.1%,14/99)。结论足部痛风石常见受累关节及韧带/肌腱分别为第一跖趾关节及跟腱,足部痛风石的沉积部位与特殊解剖部位、生物力学作用等有关。

Study of the Distribution Featuresof Tophus in Foot using Dual-energy Computed Tomography

Objective To evaluate the distribution of tophus in foot using dual-energy CT (DECT)and to explore the pathogenesis of gout. Methods Fifty-six patients with gout had DECT scanning of both feet. The sites of tophus deposition were categorized into groups of joint, ligament/tendon and they were recorded and analyzed in order. Results The DECT scans showed tophus involving 51/56 (91.1%) patients. In the group of joint, gout affected the first metacarpophalangeal joint (75%, 73/198) mostly, followed bythe ankle joint (33.9%, 32/198).In the group of tendon/ligament, Achillestendon was the most commonly involved (39.3%, 37/99), followed bythe peroneal tendons (16.1%, 14/99). Conclusion In foot, tophus is commonly deposited at the first metacarpophalangeal joint and Achillestendon. The patterns of tophus deposition suggest that anatomical location, biomechanical strain or other local factors may contribute to the distribution of tophus.