磁共振扩散张量成像在急性脑梗死的诊断及运动功能评估中的应用价值

目的探讨磁共振扩散张量成像(DTI)在急性脑梗死患者的诊断及运动功能评估的价值。方法分析49例不同时间窗的急性脑梗塞病人的MRI影像资料,所有病人均行常规MRI、DWI及DTT扫描,测量FA值、ADC值,DTT评估梗死灶与皮质脊髓束的关系。结果梗死不同时期,随着时间的推移FA值呈降低趋势,ADC值呈逐渐升高趋势。超急性期、急性期病灶中心区与边缘带的FA值及ADC值差异有统计学意义。根据弥散张量纤维束(DTT)成像梗死灶与皮质脊髓束关系分为不累及、受压无中断、破坏中断减少,破坏组及受压组的FA值、ADC及NIHSS评分差异具有统计学意义。结论磁共振扩散张量成像在急性脑梗死中FA及ADC值具有特征性演变规律,可评估急性脑梗死缺血半暗带情况,DTT可以显示梗死灶对皮质脊髓束的影响,有利于评估预后。

The Application Value of Diffusion Tensor Imaging in Acute Cerebral Infarction and Motor Function Evaluation

Objective To investigate the value of diffusion tensor imaging in acute cerebral infarction and motor function evaluation.Methods MRI features were analyzed in 49 patients in acute cerebral infarction with different timing. All patients underwent conventional MRI, DWI and DTT scanning. The FA value and ADC value were measured and reconstruct the corticospinal tract by DTT.Results In acute cerebral infarction, FA value continued to decline after the oneset of attack, and ADC value showed an upward trend. Difference of FA value and ADC value between the central and peripheral regions were significant in hyperacute and acute stroke. According to diffusion tensor fiber tractography (DTT) and based on the relationship between infarction and corticospinal tract, divided into not compression, compression without interruption(the compression group), disruption and decreases(the destruction groups).There has statically significant difference between two groups in FA, ADC value and NIHSS score. Conclusion Magnetic resonance diffusion tensor imaging in the acute cerebral infarction with FA and ADC value have characteristic discipline, can be assessed the ischemic penumbra. DTT can show the relationship between infarction and corticospinal tract has important value to prognosis.