100例疑似乳腺癌患者影像学筛查及确诊病例的临床特点分析

目的比较不同影像学方法对乳腺癌的筛查价值,并分析乳腺癌患者临床特点。方法以本院2014年1月-2015年12月就诊的100例疑似乳腺癌患者为研究对象,术前均行X线、超声、CT检查,以手术病理结果为金标准,比较不同影像学方法对乳腺癌诊断敏感度、特异度及准确度。同时分析手术病理证实乳腺癌患者临床特点。结果手术病理证实乳腺癌80例,良性肿块20例。乳腺癌临床病理特点方面,年龄≤35岁患者淋巴结转移率、ER阳性率、PR阳性率分别为64.71%、29.41%、32.35%,较年龄35岁患者的32.61%、65.22%、56.52%差异有统计学意义(P0.05)。乳腺癌筛查价值方面,X线诊断敏感度、准确度分别为71.25%、67.00%,较超声的85.00%、83.00%,CT的87.50%、86.00%差异有统计学意义(P0.05),且CT诊断特异度明显高于X线(P0.05)。结论超声、CT对乳腺癌诊断敏感度、准确度相比X线有明显优势,CT特异度最高。确诊乳腺癌患者不同年龄段临床病理特点存在一定的差异,年轻患者(年龄≤35岁)具有淋巴结转移率高、ER、PR阳性率低特点。

Imaging Screening of 100 Patients with Suspected Breast Cancer and Clinical Characteristics of Confirmed Cases

Objective To compare the value of different imaging methods in the screening of breast cancer, and to analyze the clinical characteristics of patients with breast cancer. Methods 100 cases of patients with suspected breast cancer who were admitted in our hospital between January 2014 and December 2015 were selected as study objects. Before surgery, all patients underwent X-ray, ultrasound and CT examination. The surgical and pathological results were taken as the golden standard to compare the sensitivity, specificity and accuracy of different imaging methods in the diagnosis of breast cancer. Meanwhile, the clinical characteristics of patients with breast cancer confirmed by surgery and pathology were analyzed. Results 80 cases with breast cancer were confirmed by surgery and pathology, and 20 cases were with benign tumors. For clinical pathological characteristics of breast cancer, the lymph node metastasis rate, positive rates of ER and PR in patients ≤ 35 years old were 64.71%, 29.41% and 32.35%, respectively. Compared with those in patients > 35 years old (32.61%, 65.22%, 56.52%), there were significant differences (P<0.05). For values in screening of breast cancer, the diagnostic sensitivity and accuracy of X-ray were 71.25% and 67.00%, respectively. Compared with those of ultrasound (85.00%, 83.00%) and CT (87.50%, 86.00%), there were significant differences (P<0.05). Besides, the specificity of CT diagnosis was significantly higher than that of X-ray (P<0.05). Conclusion The sensitivity and accuracy of ultrasound and CT in the diagnosis of breast cancer are better than X-ray, and the specificity of CT is the highest. There are differences in clinical pathological characteristics between patients diagnosed with breast cancer in different age groups. The younger patients (age ≤ 35 years old) have such characteristics as high lymph nodemetastasis rate and low positive rates of ER and PR.