| 松质骨骨折愈合方式的实验研究 |
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| 引用本文： | 陈永强 朱乃硕. 松质骨骨折愈合方式的实验研究[J]. 上海交通大学学报(医学版), 1999, 19(2): 103-106 |
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| 作者姓名： | 陈永强 朱乃硕 |
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| 作者单位： | 上海第二医科大学附属第九人民医院骨科!200011(陈永强，史定伟，裘世静，戴克戎)，复旦大学微生物和微生物工程系病毒研究室!200433(朱乃硕) |
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| 基金项目： | 国家自然科学基金!39200120 |
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| 摘 要： | 目的研究兔股骨髁间截骨后松质骨骨折愈合方式。方法采用成年新西兰兔30只。在兔股骨髁间作完全性截骨后，分别采用皮质骨和松质骨螺钉内固定。术后3d，1、2、3和6周截取标本进行光镜观察和核酸原位杂交分析。结果采用皮质骨螺钉固定时，其愈合方式主要通过编织骨修复骨小梁。采用松质骨螺钉固定，其愈合方式主要通过板层骨重建骨小梁。结论兔股骨髁间截骨后，松质骨骨折愈合存在着直接骨形成和间接骨形成两种愈合方式。
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| 关 键 词： | 松质骨骨折 骨折愈合 光镜观察 核酸原位杂交 |
Experimental Study on Fracture Healing Pattern of Cancellous Bone |
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| Chen Yongqiang, Shi Dingwei, Qiu Shijing, et al. Experimental Study on Fracture Healing Pattern of Cancellous Bone[J]. Journal of Shanghai Jiaotong University:Medical Science, 1999, 19(2): 103-106 |
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| Authors: | Chen Yongqiang Shi Dingwei Qiu Shijing et al |
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| Abstract: | Objective To study the fracture healing pattern of cancellous bone following osteotomy made between medial and lateral femoral condyle of rabbits. methods Thirty adult New Zealand rabbits were used. A complete osteotomy between the medial and lateral femoral condyle was performed, and then fixed with either conical or cancellous bone screw.The distal femoral condyle were obtained at 3 days and 1,2,3 and 6 weeks following operation and studied under light microscope as well as with in situ hybridazation technique.Results The healing of cancellous bone fixed with conical screw was accomplished with woven bone. The healing of cancellous bone fixed with cancellous screw was completed by lamellar bone. Concluhon There are two patterns of bone formation, direct and indirect,during cancellous bone healing of femoral condyle of rabbit. |
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| Keywords: | cancellous bone fracture healing light microscope in situ hybridazation |
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