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<Emphasis Type="Italic">Cryptococcus neoformans</Emphasis> Peritonitis in a Patient with Alcoholic Cirrhosis: Case Report and Review of the Literature
Authors:Email author" target="_blank">Sabine?Albert–BraunEmail author  F?Venema  J?Bausch  K–P?Hunfeld  V?Sch?fer
Institution:(1) Klinikum Aschaffenburg, Central Laboratory, Am Hasenkopf 1, 63739 Aschaffenburg, Germany;(2) Klinikum Aschaffenburg, Division of Internal Medicine II, Aschaffenburg, Germany;(3) Institute for Medical Microbiology, Johann Wolfgang Goethe University, Frankfurt/Main, Germany
Abstract:Abstract In the absence of coexisting HIV infection Cryptococcus neoformans is rarely considered in the differential diagnosis of peritonitis that occurs in patients with cirrhosis and ascites. Here, we report on a 39–year–old male, HIV–negative patient with decompensated alcohol toxic liver cirrhosis who developed a lethal intraperitoneal infection with C. neoformans. We reviewed the literature and found an additional 19 cases with culture confirmed cryptococcal peritonitis in combination with liver disease or AIDS. We suggest that awareness of this unusual but lethal entity may lead to earlier diagnosis and proper treatment.
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