| 烟碱对大鼠脑突触体摄取钙离子的影响 |
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| 引用本文： | 汪海 崔文玉. 烟碱对大鼠脑突触体摄取钙离子的影响[J]. 军事医学科学院院刊, 1996, 20(2): 88-90 |
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| 作者姓名： | 汪海 崔文玉 |
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| 作者单位： | 军事医学科学院毒物药物研究所 |
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| 摘 要： | 在大鼠脑突触体上，０．０１～１００μｍｏｌ／Ｌ的Ｎ受体激动剂烟碱可浓度依赖性地增加对同浓度４５Ｃａ２＋（１．０μｍｏｌ／Ｌ）的摄取量，并为１．０μｍｏｌ／ＬＮ受体拮抗剂美加明所对抗。相同条件下，１．０μｍｏｌ／Ｌ烟碱也可显著增加脑突触体对不同浓度４５Ｃａ２＋（０．１～１００μｍｏｌ／Ｌ）的摄取量。提示烟碱作用于脑Ｎ受体，可增加脑突触体对钙离子的摄取量
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| 关 键 词： | 烟碱 受体 大鼠 脑 突触体 钙离子 |
Effects of nicotine on synaptosomal 45 Ca 2+ uptake of rat brain |
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| Wang Hai,Cui Wenyu,Liu Chuangui Institute of Pharmacology and Toxicology,Academy of Military Medical Sciences,Beijing. Effects of nicotine on synaptosomal 45 Ca 2+ uptake of rat brain[J]. Bulletin of the Academy of Military Medical Sciences, 1996, 20(2): 88-90 |
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| Authors: | Wang Hai Cui Wenyu Liu Chuangui Institute of Pharmacology Toxicology Academy of Military Medical Sciences Beijing |
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| Affiliation: | Wang Hai,Cui Wenyu,Liu Chuangui Institute of Pharmacology and Toxicology,Academy of Military Medical Sciences,Beijing100850 |
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| Abstract: | |
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| Keywords: | nicotine receptor nicotinic brain synaptosomes calcium |
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