Evaluation of automated attenuation-based tube current adaptation for coronary calcium scoring in MDCT in a cohort of 262 patients |
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Authors: | Georg Mühlenbruch Christian Hohl Marco Das Joachim E Wildberger Christoph Suess Ernst Klotz Thomas Flohr Ralf Koos Christoph Thomas Rolf W Günther Andreas H Mahnken |
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Institution: | (1) Department of Diagnostic Radiology, University Hospital (RWTH) Aachen, Pauwelsstrasse 30, 52057 Aachen, Germany;(2) Siemens Medical Solutions, Computed Tomography, 91301 Forchheim, Germany;(3) Department of Cardiology, University Hospital (RWTH) Aachen, Aachen, Germany;(4) Applied Medical Engineering, Helmholtz Institute, RWTH-Aachen University, Aachen, Germany |
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Abstract: | The aim of our study was to evaluate attenuation-based tube current adaptation in coronary calcium scoring using ECG-gated
multi-detector-row CT (MDCT). A total of 262 patients underwent non-enhanced cardiac MDCT. Group 1 was scanned using a standard
protocol with 120 kV and 150 mAseff. Groups 2–4 were scanned using an attenuation-based dose-adaptation template (CARE Dose) with different effective reference
mAs settings (150, 180, 210 mAseff). Body-mass index (BMI) and CT-dose index values were calculated for each patient. Image noise and subjective image quality
were assessed. Regression analysis was performed, and the variation coefficient of image noise was determined. Compared to
the standard scan protocol a dose reduction of 31.1% for group 2 and 20.1% for group 3 was observed. Measurement variation
of image noise was smaller for the attenuation-based dose adaptation protocols (group 2–4) (16.2–17.1%) compared to the standard
scan protocol (32.3%). Regression analysis of groups 2–4 showed better correlation with improved dose usage based on BMI (all
P ≤ 0.001). Median image quality was “excellent” in groups 2–4 and “good” in group 1. Automated attenuation-based tube current
adaptation in coronary calcium scoring is technically feasible, can decrease patient dose, and reduces variation in image
noise as a sign of improved dose usage.
The study was supported by a START grant from the University Hospital of Aachen, Germany. |
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Keywords: | Multi-detector-row computed tomography (MDCT) Cardiac CT Coronary calcium scoring Dose reduction Tube current modulation |
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