| 阿立哌唑治疗精神分裂症的疗效与安全性分析 |
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| 引用本文： | 吴碧兰.阿立哌唑治疗精神分裂症的疗效与安全性分析[J].中国药业,2009,18(3):53-54. |
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| 作者姓名： | 吴碧兰 |
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| 作者单位： | 浙江省遂昌县人民医院,浙江,遂昌,323300 |
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| 摘 要： | 目的比较阿立哌唑与利培酮治疗精神分裂症的疗效及安全性。方法将82例精神分裂症患者随机均分为两组，分别使用阿立哌唑和利培酮治疗，疗程8周，采用阳性与阴性症状量表（PANSS）评定疗效，采用副反应量表（TESS）评定不良反应。结果两组间疗效比较差异无显著性（P〉0．05），阿立哌唑组不良反应较利培酮组少，但无明显差异（P〉0．05）。结论阿立哌唑是一种安全有效、耐受性好的抗精神病药，值得临床推广。
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| 关 键 词： | 阿立哌唑 利培酮 精神分裂症 不良反应 |
A Comparative Study of Episode Aripiprazole and Risperidone in Treatment of Episode Schizophrenia |
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| Wu Bilan.A Comparative Study of Episode Aripiprazole and Risperidone in Treatment of Episode Schizophrenia[J].China Pharmaceuticals,2009,18(3):53-54. |
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| Authors: | Wu Bilan |
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| Institution: | Wu Bilan (Suichang County People＇s Hospital, Suichang, Zhejiang, China 323300) |
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| Abstract: | Objective To compare the efficacy and safety of aripiprazole and risperidone in the treatment of episode schizophrenia. Methods 82 cases of episode schizophrenia were equally divided into two groups and treated with aripiprazole and risperidone respectively. The curative efficacy and the adverse effects were evaluated by PANSS and TESS respectively. Results Both medicines had comparable efficacy. The incidence of adverse effects in the aripiprazole group was lower than that in the risperidone group without significant difference. Conclusion Aripiprazole is as effective as risperidone for treating episode schizophrenia with lower adverse effects. |
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| Keywords: | aripiprazole risperidone schizophrenia adverse effect |
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