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胰腺癌淋巴结转移的特性及手术治疗
引用本文:傅德良. 胰腺癌淋巴结转移的特性及手术治疗[J]. 上海医药, 2014, 0(8): 3-7
作者姓名:傅德良
作者单位:复旦大学附属华山医院胰腺外科复旦大学胰腺病研究所,上海200040
基金项目:上海市优秀学科带头人计划(08XD14010);卫生部临床重点学科项目(2007-2010);卫生部临床重点专科项目(2012-2014)
摘    要:淋巴结转移是胰腺癌转移的主要方式,也是影响预后的重要因素。本文回顾胰头癌淋巴结转移发生的可能途径和转移特性,着重讨论胰头癌淋巴结手术清扫的范围和利弊,目前有关淋巴结清扫的争议、详尽的淋巴结获取分析和准确度肿瘤分期以及更积极的多学科肿瘤治疗是将来胰腺外科努力的发展方向。

关 键 词:胰腺癌  淋巴结转移  扩大的淋巴结清扫  手术治疗

The characteristics of lymph node metastasis and its surgical procedure
FU Deliang. The characteristics of lymph node metastasis and its surgical procedure[J]. Shanghai Medical & Pharmaceutical Journal, 2014, 0(8): 3-7
Authors:FU Deliang
Affiliation:FU Deliang (Department of Pancreatic and Hepatobiliary Surgery of Huashan Hosptial Affiliated to Fudan University, Pancreatic Cancer institute of Fudan University, Shanghai 200040, China)
Abstract:Lymph node metastasis is a common phenomenon with the positive lymph nodes being distributed over a wide range via a complex pathway, and the lymph node status is one of the most important independent factor inlfuencing the long-time survival in patients with resectable tumors. The detailed pattern and characteristic of lymph node metastasis in patients with pancreatic head cancer were reviewed. There is still a lot of debate about the beneift of extended lymphadenectomy, because pancreatic cancer frequently metastasizes to distant LNs via a complex pathway and develops into systemic disease. Accurate localization and detailed examination of the resected specimen are required for better staging and mode of lymph node metastasis. Aggressive multimodality therapy, including neoadjuvant therapy, is essential to improve the long-term survival of patients at substantial risk of distant.
Keywords:pancreatic cancer  lymph node metastasis  extended lymphadenectomy  surgical procedure
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