Molecular Evidence of Mother-to-Infant Transmission of Hepatitis G Virus among Women without Known Risk Factors for Parenteral Infections |
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| Authors: | Clara Men ndez, Jos -Marí a S nchez-Tapias, Pedro-Luis Alonso, Mireia Gim nez-Barcons, Elizeus Kahigwa, John-Jairo Aponte, Hassan Mshinda, Margarita-Marí a Navia, Marí a-Teresa Jim nez de Anta, Juan Rod s, Juan-Carlos Saiz |
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| Affiliation: | Liver Unit, Department of Medicine, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Hospital Clinic, Barcelona, Spain. |
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| Abstract: | Hepatitis G virus (HGV) RNA was detected in 18 of 133 pregnant women from Tanzania without known risk factors for HGV infection and in 7 of 18 children born to HGV RNA-positive mothers. Molecular evidence of mother-to-infant transmission was obtained only for three of seven children. HGV RNA was also detected in 4 of 42 children born to non-HGV-infected women. Thus, mechanisms other than materno-filial may play an important role in HGV transmission during early childhood. |
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