围绝经期女性疑似冠心病患者冠状动脉特点分析

目的 探讨疑似冠心病女性患者绝经前后的冠心病危险因素及冠脉病变特点.方法 纳入2009年1月~2012年9月临床疑似冠心病的围绝经期女性111例,根据是否绝经分为绝经前组（n=42）和绝经后组（n=69）,比较两组患者存在的冠心病危险因素（包括：高血压、糖尿病、高血脂、冠心病家族史）以及冠脉造影结果的差异.结果 与绝经前组相比,绝经后组患者存在冠心病危险因素的比例更高（P＜0.05）、冠脉复杂病变比例更高（59.42% vs.28.57%,P＜0.05）;但冠脉简单病变的比例则无显著差异（40.57% vs.40.48%,P＞0.05）.结论 疑似冠心病女性患者中绝经后的患者冠脉复杂病变比例显著增加,但冠脉简单病变的几率无改变.

Features of coronary heart disease in female patients during perimenopause

Objective To discuss the risk factors of coronary heart disease （CHD） and CHD features in the female patients with suspected CHD during perimenopause. Methods The female patients （n=l 11） were chosen from Jan. 2009 to Sept. 2012, and divided into pre-menopause group （n=42） and post-menopause group （n=69）. The differences in CHD risk factors （including hypertension, diabetes, hyperlipidemia, CHD family history） and results of coronary angiography （CAG） were compared between two groups. Results Compared with pre- menopause group, the percentage of CHD risk factors were higher （P〈0.05）, and ratio of coronary complex lesions was much higher （59.42% vs. 28.57%, P〈0.05） in post-menopause group, but ratio of coronary simple lesions had no significant difference between two groups （40.57% vs. 40.48%, P〉0.05）. Conclusion Among the female patients with suspected CHD, the percentage of coronary complex lesions increases but ratio of coronary simple lesions has no changes in those after menopause.