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麝香保心丸对合并高脂血症心脏X综合征患者的临床疗效
引用本文:张武宁,胡著涛,高晓东,彭雪梅,张学功.麝香保心丸对合并高脂血症心脏X综合征患者的临床疗效[J].中国循证心血管医学杂志,2013(3):285-287.
作者姓名:张武宁  胡著涛  高晓东  彭雪梅  张学功
作者单位:北京市房山区第一医院,北京102400
摘    要:目的 观察常规治疗联合麝香保心丸对合并高脂血症心脏X综合征患者的近期临床疗效.方法 纳入56例合并高脂血症的心脏X综合征患者,随机分为观察组(麝香保心丸+常规治疗)28例和对照组(常规治疗)28例,治疗6周后观察其临床总有效率,包括治疗前后患者胸痛发作次数,舌下含服硝酸甘油用量,运动平板试验总时间,ST段压低最大值时间以及C-反应蛋白(CRP)和血脂水平指标的变化.结果 观察组与对照组临床总有效率分别为92.86%和71.43%,差异有统计学意义(P<0.05).与对照组相比,观察组上述六项指标均明显改善,差异有统计学意义(P<0.05或P<0.01).结论 常规治疗基础上联用麝香保心丸可以进一步改善心脏X综合征的近期疗效.

关 键 词:麝香保心丸  心脏X综合征  高脂血症  C-反应蛋白  运动平板试验

Curative effect of Shexiang Baoxin Wan in patients with cardiac syndrome X complicating hyperlipidemia
Authors:ZHANG Wu-ning  HU Zhu-tao  GAO Xiao-dong  PENG Xue-mei  ZHANG Xue-gong
Institution:(First Hospital of Fangshan District, Beijing 102400, China.)
Abstract:Objective To observe the short-term curative effect of routine treatment combining Shexiang Baoxin Wan in the patients with cardiac syndrome X (CSX) complicating hyperlipidemia. Methods The patients (n=56) were randomly divided into observation group (Shexiang Baoxin Wan combining routine treatment) and control group (routine treatment, each n=28). After treatment for 6 weeks, the total effective rate, times of chestpain attack, dose of sublingual nitroglycerin, total time of treadmill exercise test (TET), time of ST-segment maximum depression and changes of C-reactive protein (CRP) and blood lipid parameters were observed in two groups before and after treatment. Results The total effective rate was 92.86% in observation group and 71.43% in control group (P〈0.05). All of above-mentioned indexes were significantly improved in observation group compared with control group (P〈0.05 or P〈0.01). Conclusion Routine treatment combining Shexiang Baoxin Wan can promote further the short-term curative effect on CSX.
Keywords:Shexiang Baoxin Wan  Cardiac syndrome X  Hyperlipidemia  C-reactive protein  Treadmill exercise test
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