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Content of acid proteins in neuron and glial cell nuclei of the rat hypothalamus during cold adaptation
Authors:L. V. Mogil'nitskaya  L. Z. Pevzner
Abstract:The content of acid proteins in nuclei of neurons and glial satellite cells in the medial preoptic region and supraoptic nucleus of the rat hypothalamus was studied by two-wave cytospectrophotometry on the 1st, 3rd, 7th, and 15th days of adaptation of the animal to cold (temperature 2–4°C). Cooling led to an initial decrease in the content of nuclear proteins in the whole neuronal-neuroglial system of the medial preoptic region, followed by gradual restoration to normal by the 15th day of cooling. In the glial cells of this region, before the return to normal there was a temporary increase in the content of acid proteins above the control level. In the neuronal-neuroglial system of the supraoptic nucleus a gradual accumulation of acid proteins was followed by a return to the control level. By the 15th day of the rats' stay in the cold, the content of neuronal and glial acid proteins of this nucleus fell somewhat below the control level.Department of Biochemistry, Rostov-on-Don University. Laboratory of Functional Neurochemistry, I. P. Pavlov Institute of Physiology, Academy of Sciences of the USSR, Leningrad. (Presented by Academician V. N. Chernigovskii.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 86, No. 8, pp. 187–190, August, 1978.
Keywords:adaptation  cooling  hypothalamus  neuron and neuroglia  acid proteins
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