苯那普利治疗扩张型心肌病远期疗效及生活质量观察

目的:评价苯那普利治疗扩张型心肌病的远期疗效及生活质量。方法:应用苯那普利治疗扩张型心肌病患者24例,通过对NYHA心功能分级,6 mn步行试验,自我评价疗效及预后的积分、彩色超声心动图下心功能指标(SV、CD、CI、LVDd)进行长期随访观察。结果:随着用药时间的延长,各项观察指标均有持续性改善,且以6个月以后变化更为显著(P<0.01)。结论:长期口服苯那普利可以明显改善扩张型心脏病病人的生活质量,临床疗效显著,该药可以作为扩张型心肌病治疗的常规药物。

LONG- TERM EFFECT OF BENAZEPRIL ON DILATED CARDIOMYOPATHY

Objective: To evaluate long - term effect of benazepril on dilated cardiomyopathy and patient' s life quality. Method:24 patients with dilated cardiomyopathy received benazepril therapy and they were evaluated and followed - up by NYHA cardiac function grading,6- minute walking test,therapeutic self- evaluation,prognosis integral and ultrasonic cardiac function evaluation(SV,CD,CI and LVDd). Results: With use of benazepril, the above indexes have continued to be improved and the improvements have become especially significant after 6 - month therapy ( P < 0.01) . Conclusion: Long - term oral administration of benazepril can improve life equality of cardiomyopathy patient and has a remarkable effect on cardiomyopathy. Benazepril is suggested to be used as routine medicine in clinics for the