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Assessment of Resectability of Pancreatic Carcinoma by Endoscopic Ultrasonography
作者姓名:YantaoTian  PingZhao  ChengfengWang  GuiqiWang  JianxiongWu  YiShan  YongfuShao
作者单位:DepartmentofAbdominalOncologyandEndoscopy,CancerHospital,BeijingUnionMedicalCollege,ChineseAcademyofMedicalScience,Beijing100021,China.
摘    要:OBJECTIVE To study the value of endoscopic ultrasonography (EUS) in the preoperative assessment of resectability of pancreatic carcinoma. METHODS Thirty-eight non-selected consecutive patients were prospectively investigated using EUS to determine tumor resectability. The EUS findings in each of the patients were evaluated prospectively by 2 EUS specialists. All patients were explored and resectability determinded.RESULTS Ten out of 38 cases with pancreatic carcinoma were considered to be resectable by EUS with a positive predictive value of 80% compared to findings with surgery. EUS also had a high correlation with surgical results in assessing unresectability of pancreatic carcinoma, the negative predictive. value was 96.4%. There were 2 false-positive and 1 false-negative assessments (sensitivity, 88.9% and specificity, 93.1%). The accuracy of EUS was the highest. The diagnostic accuracy of EUS, CT, MRI and sonography were 97.4%, 94.6%, 89.5%, and 73.6% respectively. CONCLUSION Endoscopic ultrasonography is an effective method to assess resectability of pancreatic carcinoma.

关 键 词:可切除度  胰腺癌  内窥镜  超声波检查法  消化系统肿瘤
收稿时间:8 July 2004
修稿时间:14 September 2004

Assessment of resectability of pancreatic carcinoma by endoscopic ultrasonography
YantaoTian PingZhao ChengfengWang GuiqiWang JianxiongWu YiShan YongfuShao.Assessment of Resectability of Pancreatic Carcinoma by Endoscopic Ultrasonography[J].Chinese Journal of Clinical Oncology,2004,1(6):393-397.
Authors:Yantao Tian  Ping Zhao  Chengfeng Wang  Guiqi Wang  Jianxiong Wu  Yi Shan and Yongfu Shao
Institution:(1) Department of Abdominal Oncology and Endoscopy, Cancer Hospital, Beijing Union Medical College, Chinese Academy of Medical Science, 100021 Beijing, China
Abstract:Objective To study the value of endoscopic ultrasonography (EUS) in the preoperative assessment of resectability of pancreatic carcinoma. Methods Thirty-eight non-selected consecutive patients were prospectively investigated using EUS to determine tumor resectability. The EUS findings in each of the patients were evaluated prospectively by 2 EUS specialists. All patients were explored and resectability determinded. Results Ten out of 38 cases with pancreatic carcinoma were considered to be resectable by EUS with a positive predictive value of 80% compared to findings with surgery. EUS also had a high correlation with surgical results in assessing unresectability of pancreatic carcinoma, the negative predictivevalue was 96.4%. There were 2 false -positive and 1 false -negative assessments (sensitivity, 88.9% and specificity, 93.1%). The accuracy of EUS was the highest. The diagnostic accuracy of EUS, CT, MRI and sonography were 97.4%, 94.6%, 89.5%, and 73.6% respectively. Conclusion Endoscopie ultrasonography is an effective method to assess resectability of pancreatic carcinoma. This work was supported by the grants from the National Education Ministry’s University Doctorate Discipline Scientific Research Fund (No. 20020023024).
Keywords:pancreas  neoplasms  endoscopic ultrasonography  resectability
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