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降钙素原与C-反应蛋白和白细胞计数在新生儿感染性疾病诊断应用
引用本文:蒋艳琼.降钙素原与C-反应蛋白和白细胞计数在新生儿感染性疾病诊断应用[J].罕少疾病杂志,2016(3).
作者姓名:蒋艳琼
作者单位:广州市花都区妇幼保健院 胡忠医院 广东 广州 510800
摘    要:目的:探析新生儿感染性疾病临床诊断中,降钙素原(PCT)、C-反应蛋白(CRP)、白细胞计数(WBC)的应用价值。方法择取本院于2015年1月-2015年12月期间收治的新生儿感染性疾病新生儿200例为实验组;另取同期检查的健康新生儿198例为参照组,对比两组新生儿的PCT、CRP以及WBC水平。结果实验组及参照组的PCT、CRP以及WBC水平组间差异统计学意义具有显著性(P<0.05),而且在新生儿感染性疾病临床诊断中,联合使用PCT、CRP、WBC,诊断灵敏度以及特异度显著优于其它检测方法。结论 PCT、CRP以及WBC可以作为新生儿感染性疾病临床诊断的有效指标,相对比其它检测方法而言,特异度、灵敏度显著。

关 键 词:降钙素原  C反应蛋白  白细胞计数  新生儿  感染性疾病诊断

Procalcitonin and C-reactive Protein and White Blood Cell Count in Neonatal Infectious Disease Diagnostic Applications
Abstract:Objective To investigate the application value of procalcitonin (PCT), C- reactive protein (CRP), white blood cell count (WBC) in the clinical diagnosis of neonatal infection diseases.Methods 200 cases of newborn diseased with infectious diseases admitted in our hospital from Jan. 2015 to Dec. 2015 had been selected as experimental group, while another 198 cases of healthy newborn examined in the meantime had been selected as control group, the two groups of newborn had been compared with each other in terms of PCT, CRP and WBC level.Results PCT, CRP and WBC levels were statistically signiifcant difference between experimental group and reference group (P<0.05). The diagnostic sensitivity and speciifcity of combined use of PCT, CRP and WBC was signiifcantly better than other detection methods in newborn infectious diseases.Conclusion PCT, CRP and WBC can be used as an effective indicator of neonatal clinical diagnosis of infectious diseases, which was great speciifcity and sensitivity compared with other detection methods.
Keywords:Procalcitonin  C-reactive Protein  Leukocyte Count  Newborns  Infectious Disease Diagnosis
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