妊娠合并麻疹46例临床分析

目的：探讨妊娠合并麻疹的流行病学特点、临床特征、对母儿的不良影响及妊娠转归。方法回顾性分析我院2012年1月-2014年12月收治的46例妊娠合并麻疹患者的流行病学史、临床资料，重点分析妊娠合并麻疹对母儿的影响和妊娠转归。结果22例早、中期妊娠者发生流产及死胎9例，占19.5%，24例晚期妊娠患者中1例早产；8例剖宫术；2例新生儿出现麻疹。结论孕早期感染麻疹，病毒影响神经系统可以使早期及晚期流产率上升，孕中、晚期感染麻疹易导致死胎和早产，中、晚期应积极治疗，减少并发症、死胎和早产的发生。

Clinical Analysis of 46 Cases of Measles Infection in Pregnancy

Objective Further understanding the epidemiologic features of pregnancy combined measles, the clinical manifestation, the maternal-fetal adverse effects, and the prognosis.Methods A retrospective study was performed on 46 cases of pregnancy combined measles during January 2012 to December 2014, the analysis was emphasized on both maternal- fetal effects and its prognosis.Results 22 of 46 cases were in first and second trimester, the other 24 cases were third trimester pregnancy. 9 of the 22 (19.5%) ended in miscarriage or still birth. 1 premature delivery, 8 c-section and 2 neonatal measles were observed among the 24 late pregnancy patients.Conclusion Viral effects on nervous system may increase the possibility of miscarriage in ifrst and second trimester when maternal infection happens in early pregnancy. Contracting in second and third trimester may lead to still birth and premature delivery. Active intervention is suggested to be given from second trimester to diminish the complication, still birth and premature birth.