探讨口腔幽门螺杆菌（HP）感染与胃HP感染的相关性及其对根除胃HP治疗的影响

目的：探讨口腔幽门螺杆菌(HP)感染与胃幽门螺杆菌感染的相关性及其对根除胃幽门螺杆菌治疗的影响。方法于2015年6月到2016年5月间，在我院选择50例出现上消化道症状初诊患者设为A组，选择50例胃HP感染根治术治疗4周后复查患者设为B组，选择40例健康人员设为对照组，所有人员均进行口腔HP感染检测，对比三组患者的检测结果。结果采取HPS检测口腔HP阳性结果为：A组38例，阳性率为76.0%；B组37例，阳性率为74.0%；对照组为40例，阳性率为80.0%。三组患者的检测结果两两对比无差异，P＞0.05。采取14C-UBT检测胃HP阳性结果为：A组阳性率为54.0%；B组阳性率为34.0%，对照组阳性率为20.0%。采取14C-UBT检测时，A组患者胃HP阳性率与B组、对照组相比明显较高，P＜0.05。采取14C-UBT检测胃HP阳性患者中，HPS口腔检测阳性为：A组阳性率为88.9%；B组阳性率为94.1%；对照组阳性率为100.0%。三组患者14C-UBT检测胃HP阳性患者中，HPS检测阳性率状况对比无差异，P＞0.05。结论不同人群中口腔HP检测水平均较高，其可能是引起胃部相关疾病发生的重要影响因素。

Discussion Oral Helicobacter Pylori (HP) Infection and Gastric HP Infection and Its Associated Impact on the Eradication of Gastric HP Treatment

Objective To investigate the oral Helicobacter pylori (HP) and its related impact on the eradication of Helicobacter pylori infection and treatment of Helicobacter pylori infection. Methods From June 2015 to May 2016, 50 cases of upper gastrointestinal symptoms in patients with newly diagnosed as group A in our hospital, select the radical mastectomy for 4 weeks were set as B group and 50 cases of gastric HP infection and 40 healthy persons as control group, all staff have to detect oral HP infection, the detection results of the three groups were compared. Results HPS detection of oral HP positive results:A group of 38 cases, the positive rate was 76%;B group in 37 cases, the positive rate was 74%, 40 patients in the control group, the positive rate of 80.0%. test results of three groups were two two compared to no difference, P>0.05. take 14C-UBT detection of gastric HP positive results:the positive rate of group A was 54%, the positive rate of B group was 34%, the positive rate of the control group Was 20.0%. Take 14C-UBT detection, a group of patients with gastric HP positive rate and B group, the control group is signiifcantly higher, P<0.05. Take 14C-UBT detection of gastric HP positive patients, oral detection of HPS positive:a group, the positive rate was 88.9%. B group, the positive rate was 94.1%, the control group, the positive rate was 100.0%. Three groups of patients with H. pylori gastric HP positive patients without HPS positive detection rate of contrast difference, P>0.05. Conclusion Oral populations HP detection levels were higher, which may be important factors cause stomach-related diseases.