| 胶原酶注射治疗腰椎间盘突出症32例随访报告 |
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| 引用本文： | 邵翔绪,卢思奇. 胶原酶注射治疗腰椎间盘突出症32例随访报告[J]. 首都医科大学学报, 1999, 20(2): 121-122 |
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| 作者姓名： | 邵翔绪 卢思奇 |
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| 作者单位： | 北京市宣武中医院骨科(邵翔绪)，首都医科大学细胞生物学系(卢思奇) |
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| 摘 要： | 为了解胶原酶治疗腰椎间盘突出症的远期疗效，对３２例病人进行了随访。其中１５例将胶原酶４００～６００Ｕ注入病变椎间盘内（盘内注射法）；１７例将胶原酶６００～１２００Ｕ注入病变椎间盘的椎间孔附近的硬膜外间隙（盘外注射法）。３年随访结果为：优１７例、良２例、可６例、劣７例（其中４例又做开放椎间盘髓核摘除术）。优良率５９．４％，有效率７８．１％，再手术率为１２．５％，未发现明显并发症。
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| 关 键 词： | 胶原酶；髓核溶解术；椎间盘突出；盘内注射；盘外注射 |
| 收稿时间： | 1998-10-26 |
| 修稿时间： | 1998-10-26 |
The Treatment of Lumbar Intervertebral Disc Protrusion Using Collagenase Injection Follow up Report of 32 Cases |
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| Shao Xiangxu,Lu Siqi. The Treatment of Lumbar Intervertebral Disc Protrusion Using Collagenase Injection Follow up Report of 32 Cases[J]. Journal of Capital Medical University, 1999, 20(2): 121-122 |
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| Authors: | Shao Xiangxu Lu Siqi |
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| Affiliation: | 1. Department of Orthopedics, Beijing Xuanwu Hospital of Traditional Chinese Medicine;2. Department of Cell Biology, Capital University of Medical Sciences |
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| Abstract: | To evaluate the forward therapeutic effect of chemonucleolysis using collagenase for the treatment of lumbar intervertebral disc protrusion, a follow up survey of 32 cases was made. All the patients were hospitalized and treated with this method. Of the cases, 15 were treated with intradisc injection method, i. e. the injection with 400600 U of the enzyme was given into the intervertebral disc and 17 with extradisc injection method, i. e. the injection with 6001 200 U of the enzyme was given into the extradural space. Results: 17 showed excellent results, 2 good, 6 fair and 7 poor. Totally, the injection treatment of collagenase gave an excellent and good rate of 59.4%, and an effective rate of 78.1%. The surgical exploration rate was 12.5%. |
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| Keywords: | lumber intervertebral disc protrusion collagenase chemonucleolysis intradisc injection extradisc injection |
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