Protein A-coated erythrocyte binding to cell surface antigens: Application to quantitate retrovirus infectivity in vitro |
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| Authors: | Thomas Fitting David Kabat |
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| Affiliation: | Department of Biochemistry, School of Medicine, University of Oregon Health Sciences Center, Portland, Oregon 97201, USA |
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| Abstract: | Fibroblasts infected with murine leukemia virus (MuLV) bind erythrocytes coated with protein A to form rosettes in the presence of MuLV-specific antisera. This method, which is potentially applicable to any retrovirus and susceptible cell, has been specifically adapted as a focus assay for quantitating both ecotropic and xenotropic MuLV. |
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| Keywords: | To whom reprint requests should be addressed. |
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