Glycinothricin, a new streptothricin-class antibiotic from Streptomyces griseus. |
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Authors: | Y Sawada S Kawakami H Taniyama |
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Abstract: | Glycinothricin is a streptothricin-class antibiotic obtained for the first time from the culture broth of a strain of Streptomyces griseus. Glycinothricin, the deformimino derivative of antibiotic LL-AB664, gives N-methylstreptolidine, N-methyl-D-glucosamine and glycine on acid hydrolysis. In comparison with LL-AB664, glycinothricin is less active against gram-positive and gram-negative bacteria and less toxic to mice. |
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