| 板栗花中两个新黄酮苷类化合物板栗花中两个新黄酮苷类化合物 |
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| 引用本文： | 王嗣,唐文照,丁杏苞.板栗花中两个新黄酮苷类化合物板栗花中两个新黄酮苷类化合物[J].药学学报,2004,39(6):442-444. |
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| 作者姓名： | 王嗣 唐文照 丁杏苞 |
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| 作者单位： | 山东省医学科学院,药物研究所,山东,济南,250062 |
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| 摘 要： | 目的研究板栗花的活性成分。方法应用硅胶柱色谱和薄层色谱进行分离,应用波谱学方法进行结构鉴定。结果分离得到两个黄酮苷类化合物,分别鉴定为山萘酚-3-O-(6″-反式-对-香豆酰基)-α-D-甘露吡喃糖苷(1)和山萘酚-3-O-(6″,4″-双-反式-对-香豆酰基)-α-D-甘露吡喃糖苷(2)。结论化合物1,2均为新化合物,命名为栗苷A和栗苷B。
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| 关 键 词： | 板栗花 活性成分 栗苷A 栗苷B |
| 收稿时间： | 2003-06-30 |
Two new flavonoids from the flower of Castanea mollissima Blume |
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| WANG Si,TANG Wen-zhao,DING Xing-bao.Two new flavonoids from the flower of Castanea mollissima Blume[J].Acta Pharmaceutica Sinica,2004,39(6):442-444. |
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| Authors: | WANG Si TANG Wen-zhao DING Xing-bao |
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| Institution: | Institute of Materia Medica, Shandong Academy of Medical Science, Jinan 250062, China. |
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| Abstract: | AIM: To study the bioactive constituents from the flower of Castanea mollissima Blume. METHODS: Compounds were isolated and purified by column chromatography on silica gel and polyamide. Structures were determined by various spectroscopic data,including UV, IR, 1H and 13CNMR, EIMS and FABMS, 1H-13C-COSY and HMBC. RESULTS: Two compounds were isolated from the ethyl acetate fraction of 95% ethanol extract and the structures were elucidated as kaempferol-3-O-6"-(E)-p-coumaroyl]-alpha-D-mannopyranoside (1) and kaempferol-3-O-6", 4"-di-(E)-p-coumaroyl]-alpha-D-mannopyranoside (2). CONCLUSION: Compounds 1 and 2 are new compounds, named castanoside A and B respectirely. |
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| Keywords: | Castanea mollissima Blume active constituent castanoside A castanoside B |
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