| 尿液肝素结合蛋白在ICU住院患者尿路感染中的诊断价值 |
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| 引用本文： | 毕晓洁,薛彩霞,陈迈,吴西军. 尿液肝素结合蛋白在ICU住院患者尿路感染中的诊断价值[J]. 当代医学, 2019, 25(4): 1-4 |
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| 作者姓名： | 毕晓洁 薛彩霞 陈迈 吴西军 |
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| 作者单位： | 河南省洛阳正骨医院(河南省骨科医院)医学检验中心,河南 洛阳,471000;贵州医科大学免疫学教研室,贵州医科大学组织工程与干细胞研究中心,中国医学科学院成体干细胞转化研究重点实验室,贵州 贵阳 550000 |
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| 摘 要： | 目的探讨尿液肝素结合蛋白在ICU住院患者尿路感染(UTI)中的诊断价值,为其临床诊疗提供参考依据。方法选取2017年10月至2018年5月入住本院ICU的患者81例,根据患者尿液细菌定量培养及实验室检查,将患者分为UTI组(40例)、可疑UTI组(21例)、非UTI组(20例),纳入同期健康体检者作为对照组(25例),比较4组受试者各实验室指标,分析其对ICU住院患者尿路感染的诊断价值。结果与对照组和非UTI组相比,UTI组患者尿液肝素结合蛋白(U-HBP)、尿白细胞酯酶(U-LE)、尿亚硝酸盐(U-NIT)、尿白细胞计数(U-WBC)显著升高,差异具有统计学意义(P<0.05);与可疑UTI组相比,UTI组U-HBP显著升高,差异具有统计学意义(P<0.05);与对照组和非UTI组相比,可疑UTI组U-HBP、U-LE、U-NIT、U-WBC显著升高,差异具有统计学意义(P<0.05)。ROC曲线显示,U-HBP曲线下面积为0.904,高于U-LE、U-NIT、UWBC;尿液细菌定量培养菌落计数(CFU)与U-HBP、U-LE、U-NIT、U-WBC相关系数分别为:0.865、0.730、0.712、0.752。结论 U-HBP对ICU住院患者尿路感染早期诊断具有较高的参考价值。
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| 关 键 词： | 肝素结合蛋白 尿路感染 早期诊断 尿液 |
Diagnostic value of urine heparin-binding protein in ICU inpatients with urinary tract infection |
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| Bi Xiaojie,Xue Caixia,Chen Mai,Wu Xijun. Diagnostic value of urine heparin-binding protein in ICU inpatients with urinary tract infection[J]. Contemporary Medicine, 2019, 25(4): 1-4 |
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| Authors: | Bi Xiaojie Xue Caixia Chen Mai Wu Xijun |
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| Affiliation: | (Testing center of Luoyang Orthopedic Hospital of Henan Province,Orthopedic Hospital of Henan Province,Luoyang,Henan,471000,China;Department of immunology in guizhou medical university,Center for tissue engineering and stem cell research in guizhou medical university,Key laboratory of adult stem cell transformation research in Chinese academy of medical sciences,Guiyang,Guizhou,550000,China) |
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| Abstract: | Bi Xiaojie;Xue Caixia;Chen Mai;Wu Xijun(Testing center of Luoyang Orthopedic Hospital of Henan Province,Orthopedic Hospital of Henan Province,Luoyang,Henan,471000,China;Department of immunology in guizhou medical university,Center for tissue engineering and stem cell research in guizhou medical university,Key laboratory of adult stem cell transformation research in Chinese academy of medical sciences,Guiyang,Guizhou,550000,China) |
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| Keywords: | Heparin-binding protein Urinary tract infectio Early diagnosis Urine |
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