思力华联合舒利迭治疗对稳定期COPD患者肺功能的影响

目的探讨思力华联合舒利迭治疗对稳定期慢性阻塞性肺疾病（COPD）患者肺功能的影响。方法将82例稳定期COPD患者随机分为两组,各41例。对照组给予舒利迭吸入治疗,观察组给予思力华联合舒利迭吸入治疗。疗程均为3个月,观察两组治疗前后血气分析变化及肺功能指标变化。结果治疗前两组pH、PaO2、PaCO2、SaO2、FEV1、FVC比较差异均无统计学意义（P〉0.05）;治疗3个月后,观察组PaO2、SaO2、FEV1、FVC均高于对照组（P〈0.01）,PaCO2低于对照组（P〈0.01）。结论思力华联合舒利迭治疗可有效改善呼吸道通气状态,保护肺功能,疗效确切,值得临床推广应用。

The impact of seretide combined with tiotropium on lung function of patients with stable COPD

Objective To study effect of seretide combined with tiotropium on lung function of patients with stable COPD.Methods Eighty-two patients with moderately severe stable COPD were divided into two groups at random. Patients in control group were given tiotropium and those in observation group were given seretide and tiotropium. The treatment time was 3 months. Blood gas analysis and lung function indexes were compared. Results Before treatment,there were no statistical differences in pH,PaO2,SaO2,FEV1 and FVC between the two groups before treatment. After 3 months＇ treatment,PaO2,SaO2,FEV1 and FVC in the observation group were higher than those of control group,while PaCO2 was lower than that of control group. Conclusion Seretide combined with tiotropium can improve respiratory ventilation condition,protect pulmonary functions and can be used in clinical treatment.