Corticosteroid dependent and independent effects of a cannabinoid agonist on core temperature,motor activity,and prepulse inhibition of the acoustic startle reflex in Wistar rats |
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| Authors: | Avdesh?Avdesh Vincent?Cornelisse Email author" target="_blank">Mathew?Thomas?Martin-IversonEmail author |
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| Institution: | (1) School of Pharmacology and Medicine, The University of Western Australia, Perth, Western Australia, Australia;(2) Centre for Clinical Research in Neuropsychiatry, Graylands Hospital, The University of Western Australia, Perth, Western Australia, Australia; |
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| Abstract: | Rationale There are inconsistent reports on the effects of cannabinoid agonists on prepulse inhibition of the startle reflex (PPI) with
increases, decreases, and no effects. It has been hypothesized that the conflicting observations may be as a result of modulation
of the effects of cannabinoid agonists by the regulation of corticosteroid release. |
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