血尿酸与儿童原发性高血压相关性研究

目的：探讨血尿酸与儿童原发性高血压的关系。方法：经临床初次诊断的原发性高血压儿童60例，45例血压正常儿童作为对照，尿酸酶法测定以上两组人员血尿酸。结果：高血压组患者血尿酸显著高于对照组（P〈0．01），血尿酸与收缩压和舒张压直接相关（r=0．8041，P〈0．01；r=0．6503，P〈0．01）。结论：原发性高血压儿童血尿酸显著增高，血尿酸在高血压发展中可能起致病作用。

Study of Correlation between Serum Uric Acid and Primary Hypertension in Children

Objective:To study the correlation between serum uric acid(UA) and primary hypertension in children.Methods:Serum levels of UA were measured in 63 children with untreated primary hypertension and 40 normotensives.Results:Serum levels of UA increased in hypertensive patients than those in controls(P<0.01). Serum levels of UA directly correlated with systolic(r=0.804 1,P<0.01) and diastolic(r=0.650 3,P<0.01) pressures in controls and in subjects with primary hypertension.Conclusion:Serum level of UA is directly correlated with blood pressure in untreated children and serum UA might play a pathogenic role in the development of primary hypertension.