亚低温对心肺复苏后患者神经功能状况及生活质量的影响

目的　探讨亚低温对心肺复苏后患者神经功能状况及生活质量的影响及其机制。方法　采用格拉斯哥昏迷评分 (GCS)、神经功能缺损评分 (NFI)、Barthel指数 (MBI)及生活质量评分 (QOL)对心肺复苏后患者的神经功能状况及生活质量进行评定 ,并观察亚低温对他们的影响。结果　在心肺复苏后第7d ,亚低温组GCS评分明显比常规治疗组高 (P <0 0 5 ) ;在复苏后第 12周和 2 4周 ,亚低温组NFI评分及QOL评分均明显较常规治疗组低 (P <0 0 5 ) ,MBI评分明显较常规治疗组高 (P <0 0 1)。结论　亚低温可改善心肺复苏后患者的神经功能状况 ,提高患者的生活质量

Effects of mild hypothermia treatment on the neurologic functional status and quality of life in patients after cardiopulmonary resuscitation

Objective To observe the effects of mild hypothermia treatment on the neurologic functional status and quality of life in patients who were cardiopulmonnary resuscitated(CPR) successfully.Methods The questionnaires of Glasgow coma scale(GCS),neurologic functional insufficiency(NFI),modified Barthel index(MBI),and quality of life(QOL)scores were used to evaluate the neurologic functional status and quality of life.The effects of mild hypothermia on these parameters were observed.Results 7 days after CPR,the GCS score was higher in mild hypothermia group than in control group.12 weeks and 24 weeks after CPR,the scores of NFI and QOL were lower in mild hypothermia group than in control group,while the score of MBI was higher .Conclusion The neurological functional status and quality of life in patients after CPR can be improved by mild hypothermia treatment. [